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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12545685 B1

PDFFull Text
Date of Patent:
Feb. 10, 2026

Filed:

Aug. 15, 2023

Dispiropyrrolidine derivatives

Applicant:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Inventors:

Yuuichi Sugimoto, Tokyo, JP;

Kouichi Uoto, Tokyo, JP;

Takanori Wakabayashi, Tokyo, JP;

Masaki Miyazaki, Tokyo, JP;

Masaki Setoguchi, Tokyo, JP;

Toru Taniguchi, Tokyo, JP;

Keisuke Yoshida, Tokyo, JP;

Akitake Yamaguchi, Tokyo, JP;

Shoko Yoshida, Tokyo, JP;

Assignee:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Attorney:

Polsinelli PC

Primary Examiner:

Ana Z Muresan

Int. Cl.
CPC ...
C07D 487/20 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); C07D 471/20 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
C07D 487/20 (2013.01); A61K 9/14 (2013.01); A61K 9/1623 (2013.01); A61K 9/1652 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); C07D 471/20 (2013.01); C07D 487/10 (2013.01);
Abstract

The present invention provides a dispiropyrrolidine derivative represented by the following formula (1), which has various substituents, inhibits interaction between Mdm2 protein and p53 protein and exhibits anti-tumor activity, wherein R, R, R, ring A, and ring B in formula (1) respectively have the same meanings as defined in the specification.

Find Patent Forward Citations

Sugimoto, Yuuichi. (2026). Dispiropyrrolidine derivatives (U.S. Patent No. 12545685). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12545685

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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