The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2026
Filed:
Dec. 16, 2021
Applicant:
Breye Therapeutics Aps, Hørsholm, DK;
Inventors:
Paolo Pevarello, Bresso, IT;
Mariangela Sodano, Bresso, IT;
Valentina Cusano, Bresso, IT;
Francesco Piscitelli, Bresso, IT;
Domenica Torino, Bresso, IT;
Rocco Vitalone, Bresso, IT;
Ali Munaim Yousif, Bresso, IT;
Oleksii Artamonov, Cracow, PL;
Assignee:
Breye Therapeutics ApS, Hørsholm, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01);
Abstract
The present invention relates to novel 1,4-substituted piperidine compounds of formula (I) having P2X7 receptor (P2X7) antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans.