The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2026

Filed:

Dec. 22, 2021
Applicant:

Baylor College of Medicine, Houston, TX (US);

Inventors:

Damian Winston Young, Houston, TX (US);

Mirjana Maletic-Savatic, Houston, TX (US);

Prasanna Kandel, Houston, TX (US);

Fatih Semerci, Houston, TX (US);

Srinivas Chamakuri, Houston, TX (US);

Assignee:

BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); A61P 25/00 (2006.01); C07D 241/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61P 25/00 (2018.01); C07D 241/04 (2013.01);
Abstract

Small molecules acting through the ligand binding domain of nuclear receptor TLX (NR2E1) are disclosed, as well as the use thereof for promoting neurogenesis and treating disorders associated with nuclear receptor TLX, including neurological disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula II as described herein, and pharmaceutically acceptable salts or isomers thereof.


Find Patent Forward Citations

Young, Damian. (2026). Small-molecule modulators of the orphan nuclear receptor tlx (U.S. Patent No. 12545657). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12545657

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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