The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2026

Filed:

Apr. 26, 2021
Applicant:

Jiangsu University, Zhenjiang, CN;

Inventors:

Xu Zhang, Zhenjiang, CN;

Jiahui Zhang, Zhenjiang, CN;

Cheng Ji, Zhenjiang, CN;

Hui Shi, Zhenjiang, CN;

Wenrong Xu, Zhenjiang, CN;

Hui Qian, Zhenjiang, CN;

Assignee:

JIANGSU UNIVERSITY, Zhenjiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 47/52 (2017.01); B03C 1/02 (2006.01); C12N 5/0787 (2010.01);
U.S. Cl.
CPC ...
A61K 47/6901 (2017.08); A61K 47/52 (2017.08); B03C 1/02 (2013.01); C12N 5/0642 (2013.01); B03C 2201/18 (2013.01); C12N 2501/06 (2013.01);
Abstract

The present disclosure provides a superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery, and a preparation method thereof, belonging to the technical field of engineered nanovesicle drug loading systems. The superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery prepared by the preparation method acts on tumor cell lines. It is found that the superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery can specifically target tumor cells, induce tumor cell apoptosis, and inhibit tumor growth. The biological preparation significantly extends a survival time of mice and improves an efficacy of drugs against cancers.


Find Patent Forward Citations

Zhang, Xu. (2026). Superparamagnetism-modified and neutrophil exosome biomimetic vesicle-based biological preparation for drug delivery, and preparation method thereof (U.S. Patent No. 12544452). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12544452

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