The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2026
Filed:
Apr. 27, 2020
Applicant:
Fibrobiologics, Inc., Houston, TX (US);
Inventors:
Pete O'heeron, Houston, TX (US);
Thomas Ichim, San Diego, CA (US);
Assignee:
FibroBiologics, Inc., Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/33 (2015.01); A61K 38/17 (2006.01); A61K 38/45 (2006.01); C12N 5/074 (2010.01); C12N 5/077 (2010.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
A61K 35/33 (2013.01); A61K 38/177 (2013.01); A61K 38/1793 (2013.01); A61K 38/45 (2013.01); C12N 5/0656 (2013.01); C12N 9/1276 (2013.01); C12Y 207/07049 (2013.01); C12N 5/0696 (2013.01); C12N 2506/1307 (2013.01);
Abstract
Embodiments of the disclosure include methods and compositions related to modulation of bone using particular fibroblasts. The modulation includes reducing osteoclast activity and/or activation and/or stimulating osteoblast activity. In particular cases, bone is modulated in an individual with a bone condition, such as osteoporosis. Particular fibroblasts may be delivered to reduce inflammatory cytokine production including RANK ligand.