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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12544383 B1

PDFFull Text
Date of Patent:
Feb. 10, 2026

Filed:

Mar. 10, 2025

Methods of treating migraines with a combination of a meloxicam and a rizatriptan

Applicant:

Axsome Therapeutics, Inc., New York, NY (US);

Inventor:

Herriot Tabuteau, New York, NY (US);

Assignee:

AXSOME THERAPEUTICS, INC., New York, NY (US);

Attorneys:

PROCOPIO, CORY, HARGREAVES & SAVITCH LLP

Brent Johnson

Yuefen Zhou

Primary Examiner:

Timothy P Thomas

Int. Cl.
CPC ...
A61K 31/5415 (2006.01); A61K 9/20 (2006.01); A61K 31/4196 (2006.01); A61P 9/04 (2006.01); A61P 25/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5415 (2013.01); A61K 9/2009 (2013.01); A61K 9/2027 (2013.01); A61K 9/205 (2013.01); A61K 31/4196 (2013.01); A61P 9/04 (2018.01); A61P 25/06 (2018.01);
Abstract

Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of meloxicam and/or rizatriptan for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura.

Find Patent Forward Citations

Tabuteau, Herriot. (2026). Methods of treating migraines with a combination of a meloxicam and a rizatriptan (U.S. Patent No. 12544383). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12544383

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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