The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 10, 2026

Filed:

Sep. 24, 2020
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Ling Li, Shanghai, CN;

Xuan Dai, Shanghai, CN;

Michael Dore, Quebec, CA;

Xiang-Ju Justin Gu, Shanghai, CN;

Kun Chin Liu, Shanghai, CN;

Sing Yeung Frankie Mak, Cintech IV, SG;

Yuan Mi, Shanghai, CN;

Counde Oyang, Sunnyvale, CA (US);

Julien Papillon, Cambridge, MA (US);

Wei (Vicky) Qi, Shanghai, CN;

Xiaoxia Yan, Shanghai, CN;

Zhengtian Yu, Shanghai, CN;

Ji Yue (Jeff) Zhang, Shanghai, CN;

Kehao Zhao, Newton, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01);
Abstract

Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediate by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.


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