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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12544359 B1

PDFFull Text
Date of Patent:
Feb. 10, 2026

Filed:

Nov. 19, 2020

1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors

Applicant:

Infex Therapeutics Limited, Macclesfield, GB;

Inventors:

Andrew Wilkinson, Macclesfield, GB;

Ian Cooper, Macclesfield, GB;

David Orr, Macclesfield, GB;

Jonathan Finlayson, Macclesfield, GB;

Adam Bunt, Macclesfield, GB;

Pia Appelqvist, Huddinge, SE;

Hans Wallberg, Huddinge, SE;

Fredrik Wångsell, Mölndal, SE;

James Kirkham, Cheshire, GB;

Assignee:

INFEX Therapeutics Limited, Macclesfield, GB;

Attorneys:

Foley Hoag LLP

Dana M. Gordon

Shejla S. Pollozi

Primary Examiner:

John S Kenyon

Assistant Examiner:

Sara Elizabeth Bell

Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/4025 (2006.01); A61K 31/403 (2006.01); A61K 31/407 (2006.01); A61K 31/4162 (2006.01); A61K 31/4178 (2006.01); A61K 31/427 (2006.01); A61K 31/431 (2006.01); A61K 31/438 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61P 31/04 (2006.01); C07D 207/48 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 471/08 (2006.01); C07D 487/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 31/4025 (2013.01); A61K 31/403 (2013.01); A61K 31/407 (2013.01); A61K 31/4162 (2013.01); A61K 31/4178 (2013.01); A61K 31/427 (2013.01); A61K 31/431 (2013.01); A61K 31/438 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61P 31/04 (2018.01); C07D 207/48 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 471/08 (2013.01); C07D 487/10 (2013.01);
Abstract

This invention relates to compounds of formula (I) and methods of treatment using the compounds. The compounds of the invention can be used in combination with antibacterial agents to treat bacterial infections. More specifically, the compounds of formula (I) can be used in combination with a class of antibacterial agents known as carbapenems. The novel compounds of the present invention are enzyme inhibitors and more particularly are metallo-β-lactamase inhibitors.

Find Patent Forward Citations

Wilkinson, Andrew. (2026). 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors (U.S. Patent No. 12544359). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12544359

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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