The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2026
Filed:
Sep. 05, 2019
Zhejiang University, Hangzhou, CN;
ZHEJIANG UNIVERSITY, Hangzhou, CN;
Abstract
The present invention discloses a method for realizing multi-column continuous chromatography design and analysis based on a chromatography model, and a method for realizing multi-column continuous chromatography design and analysis based on an artificial neural network. The method based on the chromatography model includes the following steps: step, experimental breakthrough curve fitting: performing fitting using a chromatography model to obtain model parameters; step: breakthrough curve prediction: substituting the model parameters into the chromatography model to obtain a breakthrough curve under different operation conditions; step, process analysis of continuous chromatography: substituting the predicted breakthrough curve and the continuous chromatography operation parameters into a continuous chromatography model to obtain performance indexes such as process productivity and resin capacity utilization; and step, operation space optimization of continuous chromatography: obtaining the operation space of the continuous chromatography design parameters based on a specific separation target. The method based on the artificial neutral network completes the respective steps above by replacing the chromatography model with artificial neural network.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile