The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2026

Filed:

Aug. 03, 2020
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Nuria A. Tamayo, Newbury Park, CA (US);

Abhisek Banerjee, Karnataka, IN;

Jian Jeffrey Chen, San Diego, CA (US);

Matthew Richard Kaller, Ventura, CA (US);

Thomas T. Nguyen, Newbury Park, CA (US);

Nobuko Nishimura, West Hills, CA (US);

Qiufen May Xue, Thousand Oaks, CA (US);

John Gordon Allen, Newbury Park, CA (US);

Michael J. Frohn, Thousand Oaks, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01);
Abstract

Amide compounds of formula (I): as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A.


Find Patent Forward Citations

Tamayo, Nuria. (2026). Kif18a inhibitors (U.S. Patent No. 12540129). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12540129

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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