The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2026
Filed:
Jun. 15, 2020
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Joshua D. Trzasko, Rochester, MN (US);
Shigao Chen, Rochester, MN (US);
Pengfei Song, Champaign, IL (US);
Chengwu Huang, Rochester, MN (US);
Armando Manduca, Rochester, MN (US);
Matthew Lowerison, Champaign, IL (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
Super-resolution ultrasound imaging of microvessels in a subject is described. Ultrasound data are acquired from a region-of-interest in a subject who has been administered a microbubble contrast agent. The ultrasound data are acquired while the microbubbles are moving through, or otherwise present in, the region-of-interest. Microbubble signals are isolated from the ultrasound data and are separated into subsets of data based on properties of the microbubbles, such as spatial-temporal hemodynamics. By localizing, tracking, and accumulating the microbubbles in each subset of data, super-resolution images of the microvessels can be generated for each subset, such that each of these images represents a sparse subset of microbubble signals. These images are combined to generate a super-resolution microvessel image.