The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Feb. 18, 2021
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Alexey Kuritsyn, San Jose, CA (US);

Mark Mcdonald, Milpitas, CA (US);

Aaron Rulison, Los Altos, CA (US);

Annette Grot, Cupertino, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/77 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6454 (2013.01); G01N 21/6486 (2013.01); G01N 2021/7786 (2013.01); G01N 2201/0873 (2013.01);
Abstract

Provided herein are highly multiplexed optical analytical systems for improved nucleic acid sequencing. The systems include a plurality of highly multiplexed optical chips, at least one optical source, and a plurality of optical delivery devices for illuminating an array of nanoscale rection regions on each of the optical chips. In use, the reaction regions contain fluorescent nucleic acid sequencing reagents and are arranged to report nucleic acid sequence information to optical detectors associated with the multiplexed optical chips in real time. The systems enable a massive increase in the scale of nucleic acid sequencing reactions capable of being performed within a single instrument without a corresponding increase in size, complexity, or cost of the instrument.


Find Patent Forward Citations

Loading…