The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

May. 29, 2020
Applicant:

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

Michael A. Helmrath, Cincinatti, OH (US);

Maxime Mickael Mahe, Reze, FR;

Holly M. Poling, Cincinatti, OH (US);

Assignee:

Children's Hospital Medical Center, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/38 (2015.01); A61P 1/00 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01); C12N 5/077 (2010.01); C12N 5/0793 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); A61K 35/38 (2013.01); A61P 1/00 (2018.01); C12M 21/08 (2013.01); C12N 5/0062 (2013.01); C12N 5/0619 (2013.01); C12N 5/0656 (2013.01); C12N 5/0679 (2013.01); C12N 2506/45 (2013.01); C12N 2513/00 (2013.01); C12N 2527/00 (2013.01); C12N 2535/00 (2013.01);
Abstract

Disclosed herein are organoid compositions that are manipulated to form shaped or elongated morphologies that more closely resemble native organ structures. These shaped organoids are advantageous for purposes such as studying organellar organization and for transplants compared to unformed organoids. Also disclosed herein are methods of producing said shaped or elongated organoid compositions.


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