The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Nov. 04, 2020
Applicant:

Corning Incorporated, Corning, NY (US);

Inventors:

Vasiliy Nikolaevich Goral, Painted Post, NY (US);

Kathleen Anne Krebs, Painted Post, NY (US);

William Joseph Lacey, North Andover, MA (US);

Mackenzie Anna Maloney, Elmira, NY (US);

Todd Marshall Wetherill, Painted Post, NY (US);

Assignee:

Corning Incorporated, Corning, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/26 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12M 33/04 (2013.01); C12M 23/20 (2013.01); C12M 25/14 (2013.01); C12M 29/10 (2013.01); C12M 33/12 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01);
Abstract

A cell culture system is provided that includes a cell culture vessel having an interior cavity to house a cell culture substrate in a cell culture space, and at least one port for at least one of fluid inlet to the interior cavity and fluid outlet from the interior cavity. The system further includes a piston having a distal end disposed in the cell culture vessel above the cell culture space, the distal end of the piston being sealed with an airtight seal within the interior cavity. The system also includes a driver coupled to the piston to move the piston so as to increase and decrease a distance between the distal end and the cell culture space. The driver can pressurize the interior cavity via actuation of the piston to harvest cells from the cell culture space through the at least one port.


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