The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2026
Filed:
Mar. 26, 2020
Applicant:
St. Jude Children's Research Hospital, Memphis, TN (US);
Inventors:
Rajendra P. Tangallapally, Collierville, TN (US);
Richard E. Lee, Cordova, TN (US);
Anne V. Edwards, Memphis, TN (US);
Charles O. Rock, Bartlett, TN (US);
Suzanne Jackowski, Bartlett, TN (US);
Mi Kyung Yun, Collierville, TN (US);
Chitra Subramanian, Cordova, TN (US);
Assignee:
St. Jude Children's Research Hospital, Inc., Memphis, TN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 403/08 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 495/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 403/08 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract
The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment.