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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12534450 B1

PDFFull Text
Date of Patent:
Jan. 27, 2026

Filed:

May. 08, 2024

Methods and compositions for targeting pd-l1

Applicant:

Aligos Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Tongfei Wu, Boortmeerbeek, BE;

Pierre Jean-Marie Bernard Raboisson, Wavre, BE;

Francois Gonzalvez, Antwerp, BE;

Antitsa Dimitrova Stoycheva, Half Moon Bay, CA (US);

Cheng Liu, Burlingame, CA (US);

Jerome Deval, Pacifica, CA (US);

David Mcgowan, Brussels, BE;

Assignee:

Aligos Therapeutics, Inc., South San Francisco, CA (US);

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

James H Alstrum-Acevedo

Assistant Examiner:

Lauren undefined Wells

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 487/10 (2006.01); C07D 491/048 (2006.01); C07D 498/10 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 487/10 (2013.01); C07D 491/048 (2013.01); C07D 498/10 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided herein are compounds that can be useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction. Also provided herein are pharmaceutical compositions of a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for the treatment of PD-L1 related diseases including but not limited to liver diseases, cancer, hepatocellular carcinoma, viral diseases, or hepatitis B.

Find Patent Forward Citations

Wu, Tongfei. (2026). Methods and compositions for targeting pd-l1 (U.S. Patent No. 12534450). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12534450

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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