The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Dec. 19, 2022
Applicant:

Celex Oncology Innovations Limited, London, GB;

Inventor:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/15 (2006.01); A61K 31/00 (2006.01); A61K 31/138 (2006.01); A61K 31/167 (2006.01); A61K 31/19 (2006.01); A61K 31/428 (2006.01); A61K 31/4458 (2006.01); A61K 31/495 (2006.01); C07D 241/04 (2006.01); C07D 277/82 (2006.01);
U.S. Cl.
CPC ...
C07D 295/15 (2013.01); A61K 31/00 (2013.01); A61K 31/138 (2013.01); A61K 31/167 (2013.01); A61K 31/19 (2013.01); A61K 31/428 (2013.01); A61K 31/4458 (2013.01); A61K 31/495 (2013.01); C07D 241/04 (2013.01); C07D 277/82 (2013.01);
Abstract

Substances and methods are disclosed for reducing or preventing metastatic behaviour in VGSC expressing cancer by the effect of at least reducing the persistent part of the voltage gated sodium channel current without eliminating the transient part. Inhibition of metastatic cell behaviours such as detachability, lateral motility, transverse migration and invasiveness is demonstrated using the known drugs ranolazine and riluzole.


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Djamgoz, Mustafa Bilgin Ali. (2026). Treatment of cancer/inhibition of metastasis (U.S. Patent No. 12534444). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12534444

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