The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Jul. 19, 2023
Applicant:

Oregon State University, Corvallis, OR (US);

Inventors:

Ines L. Paraiso, Corvallis, OR (US);

Jan Frederik Stevens, Corvallis, OR (US);

Paul R. Blakemore, Corvallis, OR (US);

Luce M. Mattio, Corvallis, OR (US);

Assignee:

Oregon State University, Corvallis, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); C07D 261/08 (2006.01);
U.S. Cl.
CPC ...
C07D 231/12 (2013.01); C07D 261/08 (2013.01);
Abstract

Representative xanthohumol derivatives have been made and have been tested in vivo in mice. Such derivatives have a number of important medicinal benefits, including improving glucose tolerance and decreasing weight gain by increasing energy expenditure and locomotor activity in treated subjects. Disclosed derivatives also may function as mitochondrial uncouplers. Representative compounds include 4-(5-(4-hydroxyphenyl)-1-methyl-1H-pyrazol-3-yl)-5-methoxy-2-(3-methylbut-2-en-1-yl)benzene-1,3-diol and 4-(5-(4-hydroxyphenyl)isoxazole-3-yl)-5-methoxy-2-(3-methylbut-2-en-1-yl)benzene-1,3-diol.


Find Patent Forward Citations

Paraiso, Ines. (2026). Xanthohumol derivatives and methods for making and using (U.S. Patent No. 12534439). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12534439

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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