The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Feb. 22, 2023
Applicant:

Pharmapotheca A, Inc., Albany, NY (US);

Inventors:

Harold Meckler, Albany, NY (US);

Darryl Cleary, Albany, NY (US);

Karl Popp, Albany, NY (US);

Heidi Schlager, Albany, NY (US);

Mozhgan Navidi, Albany, NY (US);

Joshua Malone, Albany, NY (US);

Assignee:

Pharmapotheca A, Inc., Dover, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/14 (2006.01); C07C 209/24 (2006.01);
U.S. Cl.
CPC ...
C07C 231/14 (2013.01); C07C 209/24 (2013.01); C07B 2200/07 (2013.01);
Abstract

The invention provides a non-distillative process for manufacturing amphetamine and substituted amphetamines, comprising obtaining a highly pure phosphoramidate compound, converting the highly pure phosphoramidate compound to an amphetamine sulfate compound, concentrating the amphetamine sulfate compound in isopropanol, and then salting out the amphetamine compound directly to obtain an amphetamine salt, the amphetamine salt selected from amphetamine saccharate, amphetamine sulfate, amphetamine aspartate, alkyl-amphetamine saccharate, alkyl-amphetamine sulfate, alkyl-amphetamine aspartate, aryl-amphetamine saccharate, aryl-amphetamine sulfate, aryl-amphetamine aspartate, and mixtures thereof.


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