The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Dec. 30, 2020
Applicants:

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Cornell University, Ithaca, NY (US);

Inventors:

Nai-Kong V. Cheung, New York, NY (US);

Steven M. Larson, New York, NY (US);

Sarah Cheal, New York, NY (US);

Richard Ting, Ithaca, NY (US);

Hari Krishna Kommidi, Ithaca, NY (US);

Feifei An, Ithaca, NY (US);

Brian Santich, New York, NY (US);

Assignees:

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Cornell University, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 49/00 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01); C07K 16/44 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0482 (2013.01); A61K 49/0032 (2013.01); A61K 49/0054 (2013.01); A61K 51/0495 (2013.01); A61K 51/0497 (2013.01); C07K 16/3084 (2013.01); C07K 16/32 (2013.01); C07K 16/44 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01);
Abstract

The present disclosure provides compositions and methods for the detection, and treatment of cancer. Specifically, the compositions of the present technology include multimodal fluorine-cyanine-DOTA-hapten compositions that may be complexed with a radioisotope (e.g.,Lu). Also disclosed herein are methods of using the fluorine-cyanine-DOTA-hapten compositions of the present technology in diagnostic imaging as well as pretargeted radioimmunotherapy.


Find Patent Forward Citations

Loading…