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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12533362 B1

PDFFull Text
Date of Patent:
Jan. 27, 2026

Filed:

Oct. 12, 2018

Methods for treating diseases associated with ciliopathies

Applicants:

Alexion Pharmaceuticals, Inc., New Haven, CT (US);

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Inventors:

Sophie Saunier, Paris, FR;

Luis Briseno-Roa, Paris, FR;

Soraya Sin-Monnot, Levallois-perret, FR;

Jean-Philippe Annereau, Antony, FR;

Marion Delous, Lyons, FR;

Hugo Garcia, Maisons-Alfort, FR;

Guillermo Del Angel, Lexington, MA (US);

Flora Legendre, Eaubonne, FR;

Assignees:

ALEXION PHARMACEUTICALS, INC., New Haven, CT (US);

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, Paris, FR;

Attorney:

McBee Moore & Vanik IP, LLC

Primary Examiner:

Kamal A Saeed

Assistant Examiner:

Sagar undefined Patel

Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61K 31/5575 (2006.01); A61K 31/559 (2006.01); A61K 49/00 (2006.01); A61P 13/12 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/559 (2013.01); A61K 31/5575 (2013.01); A61K 49/0008 (2013.01); A61P 43/00 (2018.01);
Abstract

Methods of treating a ciliopathy-associated disease are disclosed, including administering to a subject in need thereof an effective amount of a compound that targets at least one G-protein coupled receptor. Methods for identifying therapeutic agents for treating a disease having a ciliopathy are provided, including providing an animal model system of the ciliopathy for testing a putative therapeutic agent; administering a disruptive agent to the animal, treating the administered animal with the putative therapeutic agent, comparing the measurable phenotype of the treated animal with that of the animal without treatment, and identifying the therapeutic target for treating a ciliopathy, when the measurable phenotype of the treated animal is reduced as compared with that of the animal without treatment.

Find Patent Forward Citations

Saunier, Sophie. (2026). Methods for treating diseases associated with ciliopathies (U.S. Patent No. 12533362). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12533362

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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