The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2026

Filed:

Dec. 05, 2023
Applicant:

Glaukos Corporation, Aliso Viejo, CA (US);

Inventors:

Xiaojun Michael Liu, Lake Forest, CA (US);

James Jane-Guo Shiah, Irvine, CA (US);

Gabriella Szekely, Irvine, CA (US);

Assignee:

Glaukos Corporation, Aliso Viejo, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 31/27 (2006.01); A61K 31/46 (2006.01); A61K 31/498 (2006.01); A61K 31/5575 (2006.01); A61K 31/56 (2006.01); A61K 38/13 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4178 (2013.01); A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 31/27 (2013.01); A61K 31/46 (2013.01); A61K 31/498 (2013.01); A61K 31/5575 (2013.01); A61K 31/56 (2013.01); A61K 38/13 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01);
Abstract

Described herein are formulations including pharmaceutical agents comprising ester and/or lactone ring structures, and methods of using the same. The invention is also directed to a method and ophthalmic pharmaceutical compositions including solution and semisolid dosage forms (i.e. ophthalmic creams, gels, lotions, serums, and/or ointments) of treating a patient with various ocular diseases including presbyopia and dry eyes. The method comprising instructing a patient to apply one strip of the ophthalmic composition to the eyelids that includes pilocarpine or other active pharmaceutical ingredients containing ester and/or lactone ring structures with and without the buffering system.


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