The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2026
Filed:
Dec. 09, 2020
Applicant:
Duke University, Durham, NC (US);
Inventors:
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); A61K 9/00 (2006.01); A61P 17/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4045 (2013.01); A61K 9/0019 (2013.01); A61P 17/04 (2018.01);
Abstract
Methods for treating conditions including itch and pain are described. The methods include administering a therapeutically effective amount of an N-substituted indole Nav1.7 inhibitor to a subject in need thereof. New N-substituted indole compounds, useful as Nav1.7 inhibitors for the treatment of itch and/or pain are also provided, as well as pharmaceutical compositions containing the Nav1.7 inhibitors.