The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2026
Filed:
May. 18, 2020
Brown University, Providence, RI (US);
Rhode Island Hospital, Providence, RI (US);
Kareen L. K. Coulombe, Pawtucket, RI (US);
Cassady E. Rupert, New Haven, CT (US);
Celinda M. Kofron, Hope, RI (US);
Bum-Rak Choi, Warwick, RI (US);
Taeyun Kim, Coventry, RI (US);
Ulrike Mende, Norfolk, MA (US);
Brown University, Providence, RI (US);
Rhode Island Hospital, Providence, RI (US);
Abstract
The Cardio-Tox Tissue Engineered Model (TEEM) invention provides a robust in vitro model for cardiotoxicity evaluation using three-dimensional (3D) human heart microtissues to quantify dose-dependent changes in electromechanical activity, resulting in a comprehensive cardiotoxicity and arrhythmia risk assessment of test compounds. The invention also provides a predictive in vitro screening platform for pro-arrhythmic toxicity testing using human three-dimensional cardiac microtissues. The invention enables the screening of environmental and pharmaceutical compounds, chemicals, and toxicants to establish safe human exposure levels.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile