The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2026

Filed:

Sep. 02, 2022
Applicant:

Nautilus Biotechnology, Inc., Seattle, WA (US);

Inventors:

James Henry Joly, San Mateo, CA (US);

Torri Elise Rinker, San Francisco, CA (US);

Christina E. Inman, San Mateo, CA (US);

Assignee:

NAUTILUS SUBSIDIARY, INC., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/10 (2006.01); C40B 20/02 (2006.01); C40B 20/04 (2006.01); C40B 70/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C40B 20/02 (2013.01); C40B 20/04 (2013.01); C40B 70/00 (2013.01); G01N 33/6842 (2013.01); G01N 2440/14 (2013.01); G01N 2458/10 (2013.01);
Abstract

A method for characterizing proteins, including steps of (a) detecting a plurality of proteins, wherein individual proteins of the plurality are associated with unique identifiers, wherein the detecting distinguishes the identities of the individual proteins and the unique identifiers associated with the individual proteins; (b) digesting the proteins to form peptides, wherein the peptides from each protein are associated with the unique identifiers for the respective individual protein; (c) detecting the peptides and associated unique identifiers, wherein the detecting distinguishes characteristics of individual peptides, and wherein the detecting distinguishes unique identifiers associated with the individual peptides; and (d) correlating characteristics detected in step (c) with individual proteins detected in step (a) based on the unique identifiers associated with the individual proteins and the peptides.


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