The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2026
Filed:
Oct. 17, 2022
Morphic Therapeutic, Inc., Waltham, MA (US);
Bryce A. Harrison, Framingham, MA (US);
James E. Dowling, Lexington, MA (US);
Aleksey I. Gerasyuto, Flemington, NJ (US);
Matthew G. Bursavich, Needham, MA (US);
Dawn M. Troast, Bedford, MA (US);
Blaise S. Lippa, Newton, MA (US);
Bruce N. Rogers, Belmont, MA (US);
Cheng Zhong, Belmont, MA (US);
Fu-Yang Lin, Sudbury, MA (US);
Brian Sosa, Cambridge, MA (US);
Andrea Bortolato, Metuchen, NJ (US);
Mats A. Svensson, New York, NY (US);
Eugene Hickey, Danbury, CT (US);
Kyle D. Konze, Katonah, NY (US);
Tyler Day, New York, NY (US);
Byungchan Kim, West New York, NJ (US);
Morphic Therapeutic, Inc., Waltham, MA (US);
Abstract
Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions. The small molecule inhibitors of αvβ6 integrin have a tetrahydroquinoline moiety linked by a -alkylene-CH(F)—, -alkylene-C(F)—, -alkylene-CH(F)CH—, -alkylene-C(F)2CH—, -alkylene-O-alkylene-CH(F)—, or -alkylene-O-alkylene-C(F)— to a pyrrolidine moiety.