The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2026
Filed:
Oct. 15, 2020
Applicant:
Givaudan SA, Vernier, CH;
Inventors:
Nicolas Cocito Armanino, Baden, CH;
Agnes Bombrun, Zurich, CH;
An Chai, Shanghai, CN;
Julie Charpentier, Basel, CH;
Chun Chen, Shanghai, CN;
Roger Emter, Zurich, CH;
Marion Mathys, Duebendorf, CH;
Andreas Natsch, Uetikon, CH;
Chao Wang, Shanghai, CN;
Lijun Zhou, Shanghai, CN;
Assignee:
GIVAUDAN SA, Vernier, CH;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61P 43/00 (2006.01); A61Q 11/00 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07B 2200/07 (2013.01); C07B 2200/09 (2013.01);
Abstract
Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa. The disclosure relates to a particular class of compounds capable to activate TRPM8 ion channels. It further relates to the use of these compounds for inducing a sensation of coldness, and to consumer products comprising these compounds.