The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2026

Filed:

Sep. 02, 2021
Applicant:

C4 Therapeutics, Inc., Watertown, MA (US);

Inventors:

Christopher G. Nasveschuk, Stoneham, MA (US);

Roger Norcross, Basel, CH;

Fabian Dey, Basel, CH;

Annick Goergler, Colmar, FR;

Eric Andre Kusznir, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 403/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 403/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention provides heterocyclic compounds that bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation in a human or other host. The present invention also provides compounds that can be used as synthetic intermediates in the synthesis of bifunctional compounds used for targeted protein degradation.


Find Patent Forward Citations

Loading…