The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2026

Filed:

Nov. 26, 2020
Applicants:

Nanyang Technological University, Singapore, SG;

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Gerhard Gruber, Singapore, SG;

Roderick Wayland Bates, Singapore, SG;

Shuyi Pearly Ng, Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/4709 (2006.01); A61K 31/506 (2006.01); A61P 31/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/4709 (2013.01); A61K 31/506 (2013.01); A61P 31/06 (2018.01);
Abstract

The invention concerns a compound of formula (Ia) or (Ib) wherein Ris hydrogen or a methyl group; Ris an unsubstituted or substituted alkyl group; Ris an aryl group or a heteroaryl group, optionally substituted by one or more groups selected from halogen, alkyl or alkoxy; and, in Formula (Ia), X is CH or N and Y is NH, S or O, or, in Formula (Ib), X is NH, S or O and Y is CH or N. The invention further concerns a method of synthesizing the inventive compound, a composition comprising the inventive compound or a pharmaceutically acceptable salt thereof and bedaquiline (BDQ), an analogue of bedaquiline (BDQ) or a mixture thereof, and the use of said composition or compound for the treatment of tuberculosis.


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Gruber, Gerhard. (2026). Compounds for treating tuberculosis (U.S. Patent No. 12528793). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12528793

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