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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12528784 B1

PDFFull Text
Date of Patent:
Jan. 20, 2026

Filed:

Jun. 01, 2022

Alkynyl-(heteroaryl)-carboxamide hcn1 inhibitors

Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Bjoern Bartels, Schopfheim, DE;

Amanda Lee Dupont, Riehen, CH;

Benjamin J. Hall, Copenhagen, DK;

Jean-Yves Wach, Basel, CH;

Christian Schnider, Biel-Benken, CH;

Patrick Schnider, Bottmingen, CH;

Michael Reutlinger, Freiburg, DE;

Eoin O'connor, Basel, CH;

Eva Katrin Harde, Basel, CH;

Michael Weber, Sissach, CH;

Assignee:

HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);

Attorney:

Bradley Davis

Primary Examiner:

Kortney L Klinkel

Assistant Examiner:

Alison Azar Salamatian

Int. Cl.
CPC ...
A61P 25/00 (2006.01); A61P 25/08 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/30 (2006.01); C07D 233/90 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 233/90 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract

The present invention provides compounds of formula I wherein R, Ror Rare as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula I, pharmaceutical compositions comprising them and their use as medicaments.

Find Patent Forward Citations

Bartels, Bjoern. (2026). Alkynyl-(heteroaryl)-carboxamide hcn1 inhibitors (U.S. Patent No. 12528784). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12528784

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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