The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2026
Filed:
Nov. 02, 2020
Shandong University, Shandong, CN;
Xinyi Jiang, Jinan, CN;
Wei Du, Jinan, CN;
Chen Chen, Jinan, CN;
Jing Zhang, Jinan, CN;
Chunwei Tang, Jinan, CN;
SHANDONG UNIVERSITY, Jinan, CN;
Abstract
A PEGylated ICD inducer-IDO inhibitor nanoconjugate and a preparation method and use thereof. The nanoconjugate has a structural formula as follows: where R is H or with a weight-average molecular weight of 1000-5000. For the PEGylated ICD inducer-IDO inhibitor nanoconjugate provided in an aqueous medium, the PEGylated drug conjugate can self-assemble into a drug-based nanoconjugate, which can not only reduce non-specific accumulation in MPS-related organs, but also improve the passive targeting capability to solid tumors through the enhanced permeability and retention effect, thereby increasing the therapeutic index.