The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2026

Filed:

Jun. 27, 2019
Applicants:

Aurelio Lorico, Las Vegas, NV (US);

Denis Corbeil, Dresden, DE;

Mark F. Santos, Las Vegas, NV (US);

Germana Rappa, Las Vegas, NV (US);

Inventors:

Aurelio Lorico, Las Vegas, NV (US);

Denis Corbeil, Dresden, DE;

Mark F. Santos, Las Vegas, NV (US);

Germana Rappa, Las Vegas, NV (US);

Assignees:

TECHNISCHE UNIVERSITÄT DRESDEN, Dresden, DE;

BASCK INVEST LIMITED, Cambridge, GB;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61P 31/18 (2018.01); A61P 35/00 (2018.01); G01N 33/5035 (2013.01); G01N 33/6845 (2013.01); G01N 2500/02 (2013.01);
Abstract

The present disclosure relates generally to methods of inhibiting a tripartite VAP-A, ORP3 and Rab7 (VOR) protein complex in multicellular organisms, to methods of identifying agents which inhibit such complex and to the medical use of those agents. Inhibition of the VOR complex causes interference with at least one mechanism of intercellular communication, wherein the intercellular communication is mediated by receptor-ligand interaction and/or EVs, and viral infection involving the transport of endocytosed biomaterials to the nucleus of recipient cells.


Find Patent Forward Citations

Lorico, Aurelio. (2026). Inhibition of a tripartite vor protein complex in multicellular organisms (U.S. Patent No. 12527789). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12527789

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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