The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2026

Filed:

Jan. 07, 2021
Applicants:

University of Washington, Seattle, WA (US);

United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Wesley C. Van Voorhis, Seattle, WA (US);

Dustin James Maly, Seattle, WA (US);

Kayode K. Ojo, Seattle, WA (US);

Gayani Perera, Seattle, WA (US);

Stephen R. Plymate, Seattle, WA (US);

Cynthia Sprenger, Seattle, WA (US);

Takuma Uo, Seattle, WA (US);

Rama Subba Rao Vidadala, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01);
Abstract

This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases affected by glycolytic generation of adenosine triphosphate (ATP). More particularly, this disclosure relates to compounds and pharmaceutical compositions thereof, methods of selectively inhibiting glycolysis with these compounds, and methods of treating diseases that benefit from selective glycolysis inhibition, such as cancer.


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