The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2026

Filed:

Dec. 17, 2021
Applicants:

Universite DE Lille, Lille, FR;

Institut Pasteur DE Lille, Lille, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Inventors:

Rebecca Deprez Poulain, Lille, FR;

Ronan Gealageas, Mauges-sur-Loire, FR;

Virgyl Camberlein, Dunkirk, FR;

Charlotte Tabey Fleau, Villeneuve d'Ascq, FR;

Valentin Guillaume, Faches-Thumesnil, FR;

Damien Bosc, Haubourdin, FR;

Benoit Deprez, Lille, FR;

Pierre Sierocki, Mouvaux, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/14 (2006.01); A61K 31/453 (2006.01); A61K 45/06 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); A61K 45/06 (2013.01); C07D 409/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present disclosure relates to novel compounds of formula (I) which are useful as inhibitors of endoplasmic reticulum aminopeptidases (ERAP), in particular as inhibitors of ERAP2. The disclosure also relates to the therapeutic use of these compounds, in particular the use of these compounds in the treatment or prophylaxis of proliferative disorders, autoinflammatory disorders and autoimmune disorders.


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