The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2026
Filed:
Jun. 01, 2021
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd., Shijiazhuang, CN;
Chuanwu Zhao, Shijiazhuang, CN;
Yan Zhang, Shijiazhuang, CN;
Jinlu Yang, Shijiazhuang, CN;
Li Zhang, Shijiazhuang, CN;
Xuejiao Zhang, Shijiazhuang, CN;
Shuxiang Cui, Shijiazhuang, CN;
Qian Guo, Shijiazhuang, CN;
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Shijiazhuang, CN;
Abstract
Provided in the present invention are a compound as represented by formula (I), or a pharmaceutically acceptable salt, a tautomer, a geometrical isomer, an optical isomer, a solvate or an isotopic derivative thereof, and the use thereof. The compound of the present invention has a significant inhibitory activity on PRMT5, has a significant inhibitory effect on tumor cells and in vivo tumor models, also has a good administration performance, and has clinical application potential for preventing and/or treating diseases which are at least partially mediated by PRMT5.