The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2026
Filed:
Jun. 10, 2020
Applicant:
Kymera Therapeutics, Inc., Watertown, MA (US);
Inventors:
Nan Ji, Arlington, MA (US);
Yi Zhang, Belmont, MA (US);
Michael D. Sintchak, Winchester, MA (US);
Paul R. Fleming, Lexington, MA (US);
Assignee:
Kymera Therapeutics, Inc., Watertown, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 47/545 (2017.08); A61P 35/00 (2018.01);
Abstract
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same for the modulation of one or more SWI/SNF-related matrix associated actin dependent regulator of chromatin subfamily A (SMARCA) and/or polybromo-1 (PB-1) protein via ubiqitination and/or degradation by compounds. The compounds are bifunctional molecules that link a cereblon-binding moiety to a ligand that binds SMARCA and/or PB1 proteins.