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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12521386 B1

PDFFull Text
Date of Patent:
Jan. 13, 2026

Filed:

Dec. 11, 2019

Small molecule inhibitors of the androgen receptor activity and/or expression and uses thereof

Applicant:

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Inventors:

Christopher Hulme, Tucson, AZ (US);

Yeng-Jeng Shaw, Tucson, AZ (US);

Vijay Gokhale, Tucson, AZ (US);

Assignee:

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Attorneys:

Casimir Jones, S.C.

Robert A. Goetz

Primary Examiner:

Danah Al-Awadi

Assistant Examiner:

Chantal undefined Adlam

Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/454 (2006.01); A61K 45/06 (2006.01); C07D 213/74 (2006.01); C07D 257/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/454 (2013.01); A61K 45/06 (2013.01); C07D 213/74 (2013.01); C07D 257/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01);
Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a piperazine (or similar) structure which function as antagonists of androgen receptor activity, and their use as therapeutics for the treatment of cancer (e.g., castration-resistant prostate cancer) and other conditions characterized with androgen receptor activity and/or androgen receptor expression.

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Quick Actions:

Hulme, Christopher. (2026). Small molecule inhibitors of the androgen receptor activity and/or expression and uses thereof (U.S. Patent No. 12521386). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12521386

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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