The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2026

Filed:

Jun. 28, 2021
Applicant:

Raqualia Pharma Inc., Aichi, JP;

Inventors:

Tadashi Iida, Aichi, JP;

Atsushi Enomoto, Aichi, JP;

Yasuyuki Mizutani, Aichi, JP;

Masahide Takahashi, Aichi, JP;

Mitsuhiro Fujishiro, Aichi, JP;

Hiroki Kawashima, Aichi, JP;

Yoshihisa Matsukawa, Aichi, JP;

Takayuki Owaki, Aichi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 31/203 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C12Q 1/6841 (2018.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 31/203 (2013.01); A61K 45/06 (2013.01); A61K 48/0058 (2013.01); A61P 35/00 (2018.01); C12Q 1/6841 (2013.01); G01N 33/57438 (2013.01); G01N 2474/20 (2021.08);
Abstract

The present invention provides a method for selecting a cancer patient for whom a combination therapy with a retinoid and a cancer treatment agent is effective, which comprises a step of selecting a cancer patient having a malignant tumor with the infiltration of cancer-associated fibroblasts in the stroma. In addition, the present invention provides a medicament which comprises a cancer patient having a malignant tumor with the infiltration of cancer-associated fibroblasts in the stroma is a subject and is administered in combination of a retinoid and a cancer therapeutic agent.


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