Mapping between computed tomography and angiography for co-registration of intravascular data and blood vessel metrics with computed tomography-based three-dimensional model

Abstract

A co-registration system includes a processor circuit that determines a mapping between corresponding locations of a first 3D model of a blood vessel based on CT imaging data and a second 3D model of the blood vessel based on x-ray angiography data. The processor circuit receives, from an x-ray fluoroscopy device, x-ray fluoroscopy images of the blood vessel while an intravascular catheter/guidewire moves through the blood vessel. The processor circuit receives, from the catheter/guidewire, intravascular data representative of the blood vessel while the catheter/guidewire moves through the blood vessel. The processor circuit co-registers the intravascular data to the second 3D model based on the x-ray fluoroscopy images. The processor circuit co-registers the intravascular data to the first 3D model based on the mapping. The processor circuit outputs, to a display, the first 3D model and a visual representation of the intravascular data overlaid on the first 3D model.