The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Mar. 22, 2022
Universität Bern, Bern, CH;
Guodong Weng, Bern, CH;
Johannes Slotboom, Kaufdorf, CH;
UNIVERSITÄT BERN, Bern, CH;
Abstract
A method for generating 2π-refocusing pulses for magnetic resonance spectroscopy (MRS), and for performing spectral editing of MRS data using differential custom bandpass editing. Acquisition may be performed using echo-planar spectroscopic imaging (EPSI), for example. The 2π-refocusing is achieved using chemical-shift-selective adiabatic 2π-refocusing pulses, without spatial-selective (e.g. slice-selective) refocusing. The spectral editing method uses two data sets with different bandpass ('full' and ‘partial’) editing spectra, and takes the difference of the two edited spectra. The approach lends itself to 3D spectroscopy at Bof 7 T or higher, and permits whole brain J-coupled metabolite editing (e.g. 2HG or GABA), with greatly reduced specific absorption rate, shorter repetition time, minimal chemical-shift displacement artefacts (CDSAs), robustness to B-inhomogeneity and indifference to B-inhomogeneity compared with existing spatial-selective methods, such as MEGA.