The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Jan. 20, 2021
Applicant:
Neophore Limited, Altrincham, GB;
Inventors:
Julian Blagg, Altrincham, GB;
Jonathan Richard Anthony Roffey, Altrincham, GB;
Paul Colin Michael Winship, Saffron Walden, GB;
Gareth William Langley, Saffron Walden, GB;
Assignee:
NeoPhore Limited, Altrincham, GB;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); C07D 209/44 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); C07D 209/44 (2013.01); G01N 33/6875 (2013.01); G01N 2333/922 (2013.01);
Abstract
The present invention relates to novel probe compounds of formulae I and II defined herein. The present invention also relates to methods of synthesising these novel probe compounds and to their use in assays and screens for determining the binding of a test molecule to the ATP-binding site of a target protein, such as, for example, the Mismatch Repair (MMR) component proteins PMS2 and MLH1, or for determining the location and/or quantity of such target proteins in a biological sample.