The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Aug. 09, 2019
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Melissa C. Whiteman, Tomball, TX (US);
Joseph M. Antonello, Blue Bell, PA (US);
Leah A. Bogardus, Rahway, NJ (US);
Danila G. Giacone, Bound Brook, NJ (US);
Dengyun Sun, Whippany, NJ (US);
Amy H. Hsu, Edison, NJ (US);
Kevin B. Gurney, Morristown, NJ (US);
Leonard J. Rubinstein, Lansdale, PA (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The instant invention describes a virus reduction neutralization test (VRNT) which is a rapid, high throughput alternative to current standard low throughput and laborious neutralization assays. The VRNT utilizes imaging cytometry to count virus-infected cells at about one day post-infection (thus eliminating the wait time other assays employ allowing for viral infection cell to cell), reducing overall assay time and increasing throughput at least 15-fold.