The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2026

Filed:

Sep. 09, 2019
Applicant:

Georgetown University, Washington, DC (US);

Inventors:

Anton Wellstein, Washington, DC (US);

Ghada M. Sharif, Washington, DC (US);

Makarand Paranjape, Washington, DC (US);

Leon Der, Washington, DC (US);

Assignee:

GEORGETOWN UNIVERSITY, Washington, DC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/32 (2006.01); C12M 1/00 (2006.01); G01N 27/02 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5005 (2013.01); C12M 23/12 (2013.01); C12M 23/20 (2013.01); G01N 27/02 (2013.01); G01N 33/6851 (2013.01);
Abstract

Systems and methods for characterizing cancer cells are disclosed. In certain embodiments, the systems and methods involve coating a first chamber with ECM material and adding a first plurality of cells to the first chamber, adding media to a second chamber, and adding a second plurality of cells and media to a third chamber. The first, second, and third chambers are then clipped together to form a chamber array. The chamber array is mounted to an electric cell impedance sensing reader and impedance readouts of cell invasion are collected from the electric array at time intervals. Cells detected to invade into the second chamber are extracted and characterized.


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