The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Dec. 04, 2020
Applicant:
University of Maryland, Baltimore, Baltimore, MD (US);
Inventors:
Mordecai P. Blaustein, Lutherville, MD (US);
John Hamlyn, Columbia, MD (US);
Stephen Gottlieb, Baltimore, MD (US);
Ling Chen, Ellicott City, MD (US);
Assignee:
UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61K 31/7048 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61K 31/7048 (2013.01); A61K 39/00 (2013.01); A61K 39/395 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); G01N 2800/347 (2013.01);
Abstract
The present invention provides a method of preventing, reducing or attenuating acute kidney injury in a subject at risk of experiencing a transient increase in kidney ischemia or hypoxia, comprising administering to the subject an effective amount of an agent that binds to and neutralizes endogenous ouabain (EO).