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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12516027 B1

PDFFull Text
Date of Patent:
Jan. 06, 2026

Filed:

Mar. 05, 2021

Lappaconitine derivative and use thereof

Applicant:

Qgenetics Co., Ltd., Seoul, KR;

Inventors:

Mun Seog Chang, Seoul, KR;

Tae Hee Lee, Daejeon, KR;

Ha Young Kim, Seoul, KR;

Jung Bin Min, Seoul, KR;

Assignee:

QGENETICS CO., LTD., Seoul, KR;

Attorney:

Myers Bigel, P.A.

Primary Examiner:

John S Kenyon

Int. Cl.
CPC ...
C07D 223/32 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
C07D 223/32 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2059 (2013.01); A61K 9/4825 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 47/26 (2013.01);
Abstract

The present invention pertains to a novel lappaconitine derivative, a method for producing same, and a pharmaceutical use thereof using osteogenesis-promoting activity. The lappaconitine derivative induces the differentiation of stem cells into osteoblasts, increases bone mineral density when administered to animal models of osteoporosis, and induces bone formation in animal models of bone fracture, and thus can be advantageously used for preventing, ameliorating, or treating bone-related diseases such as osteoporosis, as well as treating non-disease fractures caused by physical trauma.

Find Patent Forward Citations

Chang, Mun. (2026). Lappaconitine derivative and use thereof (U.S. Patent No. 12516027). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12516027

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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