The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2026
Filed:
Nov. 04, 2016
Applicant:
Duke University, Durham, NC (US);
Inventors:
Bruce A. Sullenger, Durham, NC (US);
Ibtehaj Naqvi, Durham, NC (US);
Ruwan Gunaratne, Durham, NC (US);
Rebekah White, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/785 (2006.01); A61K 9/00 (2006.01); A61K 31/724 (2006.01); A61K 31/80 (2006.01); A61P 35/04 (2006.01); C08L 57/12 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 31/785 (2013.01); A61K 9/0012 (2013.01); A61K 31/724 (2013.01); A61K 31/80 (2013.01); A61P 35/04 (2018.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C08L 57/12 (2013.01); C08L 2203/02 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
Methods of treating cancer in a subject by administering a therapeutically effective amount of a polycationic polymer to the subject are provided. Methods of treating cancer in a subject by contacting a bodily fluid from a subject with a polycationic polymer are also provided. Methods of detecting cancer or metastasis of cancer by obtaining a sample from a subject and determining the level of circulating free DNA (cfDNA), cfRNA, inorganic polyphosphates or the number of exosomes or nucleosomes in the sample are also provided.