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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12514833 B1

PDFFull Text
Date of Patent:
Jan. 06, 2026

Filed:

Jul. 08, 2020

Combination of ibuprofen and tramadol for relieving pain

Applicant:

Farmalíder, S.a., Madrid, ES;

Inventors:

Antonio Portolés Pérez, Madrid, ES;

Luis Narciso Santé Serna, Madrid, ES;

María Del Rosario Salas Butrón, Madrid, ES;

Emilio Vargas Castrillón, Madrid, ES;

Carlos Calandria Pérez, Madrid, ES;

Raquel Horcajada Córdoba, Madrid, ES;

Ángel José Muñoz Ruiz, Seville, ES;

Marta Vicario De La Torre, Madrid, ES;

Nuria Sanz Menéndez, Madrid, ES;

Antonia Gómez Calvo, Madrid, ES;

José Ángel Sánchez García, Madrid, ES;

Ester Duart González, Madrid, ES;

Fernando García Alonso, Madrid, ES;

Assignee:

FARMALÍDER, S.A., Alcobendas, ES;

Attorneys:

Casimir Jones, S.C.

Tristan A. Fuierer

Primary Examiner:

Yevgeny Valenrod

Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 31/135 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/0019 (2013.01); A61K 9/1623 (2013.01); A61K 31/135 (2013.01); A61P 29/00 (2018.01);
Abstract

The present invention relates to the combination of ibuprofen in the form of a pharmaceutically acceptable salt, and tramadol, or a pharmaceutical acceptable salt thereof, for use in the treatment of pain in humans, wherein the dosage of ibuprofen in the combination is comprised between 350 mg and 450 mg and the dosage of tramadol is comprised between 35 mg and 40 mg, expressed as equivalent weight of tramadol hydrochloride. The combination is suitable for the treatment of moderate to severe pain, of chronic or acute origin, and is particularly effective for those patients suffering from more intense pain. It also relates to a pharmaceutical composition comprising said fixed-dose combination of ibuprofen and tramadol.

Find Patent Forward Citations

Portolés Pérez, Antonio. (2026). Combination of ibuprofen and tramadol for relieving pain (U.S. Patent No. 12514833). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12514833

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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