The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2026

Filed:

Apr. 28, 2021
Applicant:

University of Miami, Miami, FL (US);

Inventors:

Alice A. Tomei, Miami, FL (US);

Aaron Stock, Miami, FL (US);

Michael Lupp, Miami, FL (US);

Assignee:

University of Miami, Miami, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A61K 35/39 (2015.01); A61L 27/34 (2006.01); A61L 27/38 (2006.01);
U.S. Cl.
CPC ...
A61F 2/022 (2013.01); A61K 35/39 (2013.01); A61L 27/34 (2013.01); A61L 27/38 (2013.01); A61L 27/3804 (2013.01); A61L 2300/64 (2013.01); A61L 2420/02 (2013.01);
Abstract

Hydrodynamic methods for conformally coating non-uniform size cells and cell clusters with biomaterials for implantation, thus preventing immune rejection or inflammation or autoimmune destruction while preserving cell functionality, are disclosed. Further disclosed are reagents, apparatus, and methods for conformally coating cells and cell clusters with hydrogels that are biocompatible, mechanically and chemically stable and porous, with an appropriate pore cut-off size.


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