The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2025

Filed:

May. 31, 2019
Applicant:

Unchained Labs, Pleasanton, CA (US);

Inventors:

George G. Daaboul, Watertown, MA (US);

David S. Freedman, Newton Highlands, MA (US);

Amit Deliwala, Andover, MA (US);

Assignee:

Unchained Labs, Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2024.01); G01N 15/0205 (2024.01); G01N 33/543 (2006.01); G02B 5/28 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1456 (2013.01); G01N 15/0211 (2013.01); G01N 33/54366 (2013.01); G02B 5/285 (2013.01); G01N 2015/0238 (2013.01); G01N 2015/025 (2013.01);
Abstract

Presented herein are compositions, systems, and methods related to optical substrates that simultaneous (1) enhance a fluorescence signal emitted by a fluorophore and (2) enhance 'contrast' signal that comprises scattered signal intensity over substrate reflectivity at a non-fluorescent wavelength. In certain embodiments, the optical substrate comprises a thin, transparent, dielectric layer. In alternative embodiments, the optical substrate comprises a stack of thin, transparent dielectric layers, for example, that is designed for both specific scattering enhancement and fluorescence enhancement.


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