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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12509468 B1

PDFFull Text
Date of Patent:
Dec. 30, 2025

Filed:

Jan. 29, 2020

Quindoline compounds and uses thereof

Applicant:

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Inventors:

Laurence Hurley, Tucson, AZ (US);

Biswanath De, Tucson, AZ (US);

Venkateshwar R. Chappeta, Tucson, AZ (US);

Tracy A. Brooks, Tucson, AZ (US);

Vijay Gokhale, Tucson, AZ (US);

Cynthia Miranti, Tucson, AZ (US);

Elsa Reyes Reyes, Tucson, AZ (US);

Assignee:

Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Attorneys:

Casimir Jones, S.C.

Robert A. Goetz

Primary Examiner:

Kortney L Klinkel

Assistant Examiner:

Sophia undefined Reilly

Int. Cl.
CPC ...
C07D 487/14 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/4738 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); A61K 31/4709 (2013.01); A61K 31/4738 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61K 31/47 (2013.01);
Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quindoline (or similar) structure which function as stabilizers of G-quadruplex (G4) formation, and their use as therapeutics for the treatment of cancer (e.g., castration-resistant prostate cancer), and other conditions mediated by G4 stabilization.

Find Patent Forward Citations

Hurley, Laurence. (2025). Quindoline compounds and uses thereof (U.S. Patent No. 12509468). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12509468

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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